Recombinant human CCL21
产品编号:SB-ZR062 产品规格: 产品品牌:圣尔生物share-bio  一键复制产品信息
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CCL21 is encoded by CCL21 gene that is located in Chr.9 and shows 21-33% identity to other CC chemokines. This chemokine contains the four conserved cysteines characteristic of β chemokines plus two additional cysteines in its unusually long carboxyl terminal domain. CCL21 is highly expressed in lymph nodes of certain endothelial cells, and in the spleen and appendix. It elicits effects by binding with CCR7, having functions of T and B lymphocytes chemotaxis and inhibiting hematopoiesis. Recombinant Human Exodus-2/CCL21 is a 12.2kDa protein containing 111 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines

Product Information

Product Name

Recombinant Human Exodus-2/CCL21

(rHuExodus-2/CCL21)

Synonyms

6Ckine, Beta-chemokine Exodus-2, SLC

Source

Expressed in E. coli. 

Molecular weight

Approximately 12.2kDa, a single non-glycosylated polypeptide chain containing 111 amino acids.

Accession

O00585 Ser24-Pro134

AA Sequence

SDGGAQDCCLKYSQRKIPAKVVRSYRKQEPSLGCSIPAILFLPRKRSQAELCADPKELWVQQLMQHLDKTPSPQKPAQGCRKDRGASKTGKKGKGSKGCKRTERSQTPKGP

Purity

97% by SDS-PAGE or HPLC

Formulation

Lyophilized from a 0.2mm filtered solution in 20mM PB, 150mM NaCl, pH7.4.

Biological activity

Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human lymphocytes is in a concentration range of 10-100ng/ml.

Endotoxin level

Less than0.1EU/mg of rHuExodus-2/CCL21 as determined by LAL method

Reconstitution

Before use this product, please read the direction below carefully.

1、 This vial must be briefly centrifuged prior to opening to bring the contents to the bottom.

2、 Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0mg/ml. 

Stock solutions should be apportioned into working aliquots and stored at ≤-20. Further dilutions should be made in appropriate buffered solutions.

Storage/ Stability

For long term storage, the product should be stored -20. Please avoid repeated freeze-thaw cycles after reconstitution.

12 months from date of receipt, -20 to -70 as supplied.

1 month, 2 to 8 under sterile conditions after reconstitution.

3 months, -20 to -70 under sterile conditions after reconstitution.

THIS PRODUCT IS FOR RESEARCH, LABORATORY AND EVALUATION PURPOSE ONLY.

 

【储存条件及期限】 冻干粉于-20℃到-80℃长期保存3年,溶液状态保存期3个月,避免反复冻融。
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For research use only. Not intended for human and animal therapeutic or diagnostic use.

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